Wednesday, June 6, 2007
zomig
I haven't had a migraine for several months, but have been doing battle for two days with the latest most evil manifestation of head pain. I suppose the first point is that I am currently thankful for the migraine-free period I didn't fully appreciate until now. The second point is that yesterday I got some relief from my favourite selective 5-hydroxytryptamine 1 (5-HT 1B/1D) receptor agonist, zolmitriptan. It's nickname is Zomig and we're friends. I just took another one and hope it affords me some relief and a good night's sleep. Zomig does a little dance with my intracranial blood vessels (including the arterio-venous anastamoses) and the sensory nerves of the trigeminal system. Basically, it fights against the cranial vessel constriction and inhibits pro-inflammatory neuropeptide release. Inflammatory neoropeptide release is a real pain, but kind of fun to say out loud. Here's hoping sweet Zomig is getting to work even now.
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